There are two levels of Profile Corruption.
Level one (Damaged creation content)Edit
If it says "Part of your profile appears to be corrupt," your creations are corrupt, and you will recover from your backup. If level icons start appearing as exclamation marks, your may be at risk for creation corruption. You may also be at risk if your levels sometimes fail to load with the message "Failed to load level".
Level two (Broken Profile)Edit
Sometimes it will say it is corrupted completely.
Out of Date GameEdit
Sometimes it will think you are playing an older version of LittleBigPlanet PS Vita. First backup, then update. If the message still appears, restore from an older backup.
If you see the Delete action mapped to Template:Circle, and you receive the message "Recent changes could not be saved", the game (and profile) is corrupt, and you will need to delete your LittleBigPlanet PS Vita Game files in order to save and recover from backup.